Transformation of BALB/c-3T3 Cells: Introduction
نویسندگان
چکیده
منابع مشابه
Transformation of BALB/c-3T3 Cells: Introduction
The data and results in this series ofpapers on chemical transformation of BALB/c-3T3 cells detail a substantial effort to understand the uses and limitations of this methodology in identifying chemicals with carcinogenic potential. This project is an important portion of an effort supported by the National Toxicology Program (NTP) to develop, evaluate, and validate various in vitro and in vivo...
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متن کاملTransformation of NIH/3T3 cells by ornithine decarboxylase overexpression.
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15 صفحه اولTransformation of BALB/c-3T3 cells: I. Investigation of experimental parameters that influence detection of spontaneous transformation.
The frequency of spontaneous morphological transformation is an important variable in measuring chemical-induced transformation in BALB/c-3T3 clone A-31-1-13 cell cultures. Data from 110 experiments, which included benzo[a]pyrene control groups and other chemical treatment groups, were analyzed for factors that influenced spontaneous transformation. Spontaneous transformants demonstrated a cont...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1993
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.93101s2275